Millions of people suffer from high blood pressure or hypertension, and although powerful drugs are already available, few manage to achieve target blood pressure levels compelling researchers to find new methods to combat blood pressure. UK scientists have discovered a new way to regulate blood pressure, offering hopes of new drugs to combat strokes and heart attacks. Scientist discovered that oxidants such as hydrogen peroxide cause a bond to form between two amino acids which, in turn, activates PKG(Protein kinase G is an important protein in all tissues, but in the cardiovascular system it plays a fundamental role in blood pressure regulation). This then leads to a lowering of blood pressure. The team's novel discovery unlocks opportunities for the design of new drugs to combat high blood pressure. Also the mechanism provides new insights into how oxidant stress affects cells and tissues.

Oxidant stress not only alters blood flow, but also affects the heart's ability to contract and is involved in a wide variety of inflammatory conditions.
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